1.One of the two copies of the globin gene in a fertilized egg cell develops the mutation that results in Sickle Cell Anemia. How many copies of this version of the gene will each of the cells in the adult have?
a. none
b. one
c. two
d. three
2.What effect would a defective DNA Polymerase I have on the rate of production of Okazaki fragments?
a. increase
b. decrease
c. no effect
1. Option -B one. As one of the copies of the globin gene is mutated so an adult will receive only one set of default genes and in later life the person will be the carrier of the disease. The person may not be affected by the trait and can lead a healthy life.
2. Option - C no effect. The defective DNA Polymerase I have no effect on the rate of production of Okazaki fragments as the main function of DNA Polymerase I is to add nucleotide bases on Okazaki fragments and which is later joined by DNA ligase to form a continuous strand. The defective DNA Polymerase I causes a mutation in the strand which is a leading cause of cancer
The production of Okazaki fragments is neither increased nor decreased it remains according to the number of base pairs in one strand. However, the mutation in nucleotide base pairs occurs.
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