The liver and kidneys are major sites of gluconeogenesis.
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Question 391 pts
The LDH isozyme in heart tissue can be allosterically inhibited by high concentrations of pyruvate.
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Question 401 pts
Glycogen in skeletal muscle serves as a reservoir of blood glucose.
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Question 411 pts
Glycogen synthase is nearly inactive when it is phosphorylated.
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Question 421 pts
Protein phosphatase can reverse the action of the kinase on enzymes.
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Phosphofructokinase activity can be decreased by AMP.
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Glucagon and epinephrine are similar in that both promote glycogenolysis.
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Glucose-6-P dehydrogenase deficiency can lead to drug-induced hemolytic anemia because not enough NADH is generated.
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1. True. The liver and kidneys are the major sites of Gluconeogenesis.
Gluconeogenesis occurs in animals during starvation or other wasting conditions like Diabetes mellitus, when the organism necessarily requires glucose as a source of energy. It meets the needs of the body for glucose when carbohydrate is not available in required amount from the diet. The principal site is the liver, being responsible for 85%-95% of glucose formation. Gluconeogenesis also occurs in the cortex of kidney, but the amount formed here is small.
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