Question

Which one fact is false?

A	All GPCRs are made of three subunits

B	All GPCRs are made of proteins

C	All GPCRs operate at the membrane level

D	All GPCRs are activated by a change in conformation of their receptor

E	None of the above

Answer 1

E) none of the all

G Protein - couple receptor constitute a large protein family of receptor . Receptor that detect molecule outside the cell and activate internal transduction pathway, and ultimately cellular responses. These receptors are known as 7 transmembrane receptor because they passes membrane 7 times.

G Protein couple receptor have 3 subunits alpha, beta, gamma subunits.

All G proteins operate at membrane level

The structure of GPCRs activated are determine. These structures indicate ligand bind at excellular site, resulting in. Conformation change in cytoplasimic side of receptor. Theses receptors are activated by light sensitive compounds, odor, hormones, pheromones and neurotransmitters etc.