Question

Which enzymes hydrolyze specific ester bonds that connect the different building blocks that make up a...

Which enzymes hydrolyze specific ester bonds that connect the different building blocks that make up a phospholipid molecule?

A) phospholipid kinases
B) phospholipid phosphatases
C) phospholipases
D) phosphatidyl phosphatases
E) phospholipid dephosphorylase

Homework Answers

Answer #1

c) Phospholipases hydrolyse the specific ester bonds that connect the different building blocks which makes up a phospholipid molecule.

Phospholipases are group of enzymes either calcium dependent or calcium independent. These enzymes hydrolyze the phospholipids to fatty acids; play an important role in maintaining the membrane integrity, cell signaling functions. There are four major types of phospholipase enzymes which is differentiated based on the type of reaction they catalyze such as phospholipase A that hydrolyse acyl ester bonds at both phospholipase A1(sn1) and phospholipase A2 (sn2) position. Phospholipase B again cleaves sn1 and sn2 of acyl chains. Type C cleaves glycerophosphate bond and type D cleaves after the phosphate releasing phosphatidic acid and an alcohol. Therefore phospholipases are key players to maintain the health condition.

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