Question

This is an essential cofactor for pyruvate dehydrogenase complex and whose deficiency results in this disease.

	A.	Vitamin B1, Beriberi
	B.	Vitamin B12, Anemia
	C,	Vitamin C , Scurvy
	D.	Biotin, No deficiency noted
	E.	None of the above

What high energy intermediate in glycolysis is generated by Enolase?

	a.	None of the above
	b.	1,3-Bisphosphoglycerate
	c.	Fructose-1,6-Bisphosphate
	d.	2-Phosphoglycerate
	e.	Phosphoenolpyruvate

Answer 1

Q. Out of the four cofactors of pyruvate dehydrogenase, riboflavin, niacin, pantothenate and thiamin , thiamin is a cofactor that is Vitamin B1. The deficiency of Vitamin B1 causes a disease called Beriberi. Symptoms of Beriberi are loss of appetite, weakness, pain in limbs etc.

So, correct answer is (A) Vitamin B1, Beriberi

Q. Enolase converts 2-Phosphoglycerate to phosphoenolpyruvate by removing a water molecule. Phosphoenolpyruvate is a high energy intermediate in glycolysis.

So, correct answer is (e) Phosphoenolpyruvate

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