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Can Lentiviral transfection can serve as a vaccination tool?

Can Lentiviral transfection can serve as a vaccination tool?

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Answer:    Yes. Lentiviral transfection can serve as a vaccination tool.

Lentivirus serves as a vector that is employed as gene-transfer vectors. Their potenial high transduction efficiency is realised independent of the proliferative stage of the cells which are targeted. Lately, their transducational abilities were used on dendritic cells has hinted towards their application as vaccination vectors. They are able to transduce the dendritic cells, thereby stimulating strong responses from T-cell against the antigen that is encoded. This makes them capable of eliciting a potent cellular as well as humoral immune response.

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