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Which of the following statements is FALSE regarding the role of metabolic pathways in cancer cells?...

Which of the following statements is FALSE regarding the role of metabolic pathways in cancer cells?

A. Cancer cells rely heavily on aerobic glycolysis to produce energy.

B. Cancer cells utilize the citric acid cycle to produce biosynthetic intermediates.

C. Cancer cells may have similar metabolic activities to brown fat cells.

D. Cancer cells utilize oxidative phosphorylation for the bulk of their ATP synthesis.

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Answer #1

C. Cancer cells may have similar metabolic activities to brown fat cells.

All major pathways of carbohydrate metabolism are connected to conversions of glucose, since glucose is the main sugar in the blood and the main energy fuel in the body. The metabolic pathways are glycolysis, Oxidation of Pyruvate, Citric Acid Cycle, Pentose Phosphate Pathway, Glycogen metabolism (glycogenolysis, glycogenesis) and Gluconeogenesis.Cancer cells utilize oxidative phosphorylation for the bulk of their ATP synthesis. Glucose is the primary source of energy and is the main fuel for cellular respiration. In glucose utilization in normal conditions, 70% of ATP is known to be synthesized by oxidative phosphorylation and the rest by glycolysis.

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