Question

Which of the following apply to limb bud development

Group of answer choices (select all that apply!)

Shh signalling forms a gradient from the anterior to posterior of the limb

ZPA signaling establishes the anterior-posterior axis formation of the limb using Shh signals.

Limb development is essentially autonomous after the signaling regions have been established late in the limb bud

Limb development is essentially autonomous after the signaling regions have been established early in the limb bud

Dorsal ectoderm utilizes Wnt signals

FGF signalling forms a gradient from anterior to the posterior of the limb bud

Ventral ectoderm utlizes BMP signals

The dorsal-ventral axis is established in the limb bud by the competitive Wnt and BMP signals

The AER region determines the proximal-distal axis formation of the limb using FGF signals

Answer 1