In the circulation of blood, vessels with endothelial lining and smooth muscle cells and interestingly they interact to each other for the proper functioning and physiological process of vascular motion. In this interaction various factors involved like nitric oxide, signaling of messenger molecule like cyclic GMP but significantly it is controlled by paracrine signaling through muscle relaxing factor like EDRF and EDHF. So, in this case such kind of cell communication is crucial for the behavior of the neighboring cell. Therefore, correct option would be “Paracrine signaling” remaining choice are less relevant in the given scenario.
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