In the absence of carnitine, cells cannot use fatty acids _________
A. to synthesize triacylglycerides,
B. to form chylomicrons,
C. for energy
Nor can they _______
A. use ketone bodies for energy.
B. use ketone bodies to fuel glyconeogenesis
C. produce significant quantities of ketone bodies
Therefore, tissues and organs, such as the skeletal muscles, heart, and brain, must primarily utalize _______
A. glucose
B. fatty acids
C. amino acids
For every production under these conditions, which drives __________
A. excessive B-oxidation
B. excessive glucose uptake from the blood
C excessive glycogen synthesis
Answer:
In the absence of carnitine, cells cannot use fatty acids For energy (Option C)
Nor can they use ketone bodies for energy. (Option A)
Therefore, tissues and organs, such as the skeletal muscles, heart, and brain, must primarily utilize glucose (OptionA)
For every production under these conditions, which drives excessive glucose uptake from the blood (Option B)
Carnitine shuttle is an important carrier which transports activated fatty acids from cytosol to mitochondria for the process of Beta oxidation. In the absence of Carnitine, these fatty acids cannot be transported to mitochondria and cannot be used as a source of energy. In these conditions glucose is primarily utilized by all muscles, heart, brain, etc leading to drop in blood glucose (hypoglycemia).
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