Question

Rare autosomal dominant diseases are ________.

typically not passed on to offspring

typically more severe in homozygous recessive individuals than in homozygous dominant individuals

typically similar in severity in homozygous dominant and heterozygous individuals

typically more severe in homozygous dominant individuals

typically less severe in homozygous dominant individuals than heterozygous individuals

Answer 1

Rare autosomal dominant diseases are__________.

Answer: c. typically similar in severity in homozygous dominant and heterozygous individuals

Autosomal means: The gene for the disease is present in one of the 22 autosomal (or non sex) chromosomes.

Dominant inheritance: means an abnormal gene from one parent is enough to cause the disease. And if both alleles from two parents are dominant, then also the person will get the disease with similar severity. Severity of the disease does not depend on the number of dominant alleles in a genotype

Thus option a,b,d and e are incorrect because in these options it is mentioned that the severity of the disease will vary between the two cases (if both allele are dominant and one allele is dominant)