Question

3. Complete the table below. By ATP equivalents, I mean any deoxyribonucleotide or ribonucleotide (dATP, dCTP, dGTP, dTTP, or ATP are energetically equivalent).

Type of damage	Does it require? 1.no ATP or ATP equivalents, 2. a few ATP or ATP equivalents, or 3. many ATP or ATP equivalents	Does it require new DNA synthesis?	Repaired by which specific DNA repair system or systems?
Uncorrected mismatch from an error in DNA replication
UV-created thymine dimer
Alkylation of a base in DNA (non-bulky)
Loss of a base from DNA
Double-stranded break in DNA

Answer 1

Ans.

Type of damage	Does it require? 1.no ATP or ATP equivalents, 2. a few ATP or ATP equivalents, or 3. many ATP or ATP equivalents	Does it require new DNA synthesis?	Repaired by which specific DNA repair system or systems?
Uncorrected mismatch from an error in DNA replication	3	yes	Mismatch repair
UV-created thymine dimer	1	no	photoreactivation repair by photoreactivation enzyme(PRE)
Alkylation of a base in DNA (non-bulky)	2	no	base excision repair
Loss of a base from DNA	3	yes	SOS repair
Double-stranded break in DNA	3	yes	double - strand break repair (homologous recombination repair or non-homologous end-joining)