Question

2. A moth census on Wooded Island counted 100 black (BB) moths, 40 gray (Bb) and 60 white (bb) moths. What are the genotypic frequencies? What are the allelic frequencies? Is the population in Hardy-Weinberg equilibrium?   

4. Phenylketonuria is a severe form of mental retardation due to a rare autosomal recessive allele. About 1 in 10,000 newborn Caucasians are affected with the disease. Calculate the frequency of carriers (i.e., heterozygotes).   Note what assumption you are making.

5. A study on blood types in a population found the following genotypic distribution among the people sampled: 1101 were MM, 1496 were MN and 503 were NN. Calculate the allele frequencies of M and N, the expected numbers of the three genotypic classes (assuming random mating). Using X², determine whether or not this population is in Hardy-Weinberg equilibrium.
6. A scientist has studied the amount of polymorphism in the alleles controlling the enzyme Lactate Dehydrogenase (LDH) in a species of minnow. From one population, 1000 individuals were sampled. The scientist found the following genotype frequencies: AA = 0.080, Aa = 0.280; aa = 0.640. From these data calculate the allele frequencies of the A and a alleles in this population. Use the appropriate statistical test to help you decide whether or not this population was in Hardy-Weinberg equilibrium.

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topic Genetics

Answer 1

1.

Null hypothesis : population is under HWE.

If p value is less than 5%, than we reject null hypothesis and place an alternative hypothesis.

Alternative hypothesis : population is not under HWE.

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