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Which compliment pathway involves binding of compliment to the lipopolysaccharide layer of the bacterial cell wall?...

Which compliment pathway involves binding of compliment to the lipopolysaccharide layer of the bacterial cell wall?

Classic Pathway

Mannose-binding Lectin Pathway

Alternative Pathway
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Answer #1

Ans) The correct answer is "C" i.e Alternate pathway (Here the Factor 1 and Polysaccharide coat of Antigen activate the complement pathway unlike Classical pathway where Ag-Ab complex activates the pathway. In mannose binding lectin pathway, lectin protein from blood binds to mannose binding protein (MBP) present as glycoprotein on outer surface of bacteria.In all of these three pathways the end result is the formation of MAC or membrane attack complex for the destruction of Antigen).

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