Question

1. Aspartate is metabolized to oxaloacetate, which we know via gluconeogenesis can be used to generate PEP. Assuming the PEP then proceeds to pyruvate and acetyl CoA and enters the citric acid cycle, how much ATP could be generated from the complete oxidation of Aspartate if we assume 1 NADH produces 3 ATP, 1 FADH2 produces 2 ATP, and GTP or ATP are equivalent (1GTP=1ATP). (Also ignore the “cost” of Nitrogen removal; don’t consider the urea cycle)

2. True or false: (EXPLAIN FOR FALSE)

______Chylomicrons are produced in the intestinal cells

______Carnitine is required for shuttling Fatty acids into the cell

______Malonyl-CoA inhibits transport of Fatty acids into the mitochondria

______Insulin inhibits Fatty acid breakdown

______Odd chain fatty acids can be used to produce Succinyl CoA

______Fatty acid synthesis begins with 1 acetyl CoA and 1 Malonyl CoA

______ acidic Fatty acids are absorbed into intestinal cells via Na+-dependent transporters

Answer 1