Question

1. In fatty acid synthesis, Malonyl CoA is the activated form of acetyl CoA. What is...

1. In fatty acid synthesis, Malonyl CoA is the activated form of acetyl CoA. What is the only chemical difference between these two molecules?

2. How many HMG-CoA are used to produce cholesterol

a. 4

b. 5

c. 6

d. 8

e. 18

Homework Answers

Answer #1

ANSWER1
Although, both are derivatives of Co-A enzyme. Malonyl-CoA is 2-carbon unit where as acetyl-CoA is one carbon unit. Malonyl-CoA is syhthesised by carboxylation of acetyl-CoA in the presence of ATP. Synthesis of Malonyl-CoA is commitment step for fat synthesis and polyketides synthesis. Acetyl-CoA serves as intermediate in many chemical reactions. Acetyl CoA provides acetyl group in citric acid cycle to produce ATP and required for fatty acids breakdown.

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