Question

True or False:

The most common mechanism of activating proteins (“turning them on”) is acetylation ___

During translation, a newly arriving tRNA-amino acid enters the A site of the ribosome. ___

A gene coding for a transcription factor is an example of a regulatory gene ___

The most common mechanism of gene regulation is at the level of the control of transcription ___   

There are about 25,000 protein coding genes in the human genome __

There are more proteins in the human proteome than actual protein-coding genes ___

Answer 1

1. FALSE
The most common mechanism of activating proteins is PHOSPHORYLATION/DEPHOSPHORYLATION

2. TRUE
A-site = Aminoacyl tRNA site
During translation, a newly arriving tRNA-amino acid enters the A site of the ribosome.  

3. TRUE
A transcription factor affects the expression of its target gene

4. TRUE
Transcriptional gene regulation is the most common mechanism of gene regulation in both prokaryotes and eukaryotes.

5. TRUE
number of protein-coding genes in humans = 20000-25000

6. TRUE
Alternative splicing can generate multiple types of mature transcripts from a single type of primary transcript.
It increases the repertoire of transcriptome and proteome without affecting the genome.