Question

The Galpha subunit is active when: A. it is bound to a molecule of GTP. B....

The Galpha subunit is active when:

A. it is bound to a molecule of GTP.

B. it is bound to a molecule of GDP

C. it is bound to a molecule of cAMP

D. it is bound to a molecule of cGMP

E. all of the above are correct.

In the Pyruvate Dehydrogenase complex, the acetyl unit is passed to the coA directly from _________.

A.

biotin

B.

TPP

C.

pyruvate

D.

FAD

E.

lipoyllysine

Homework Answers

Answer #1

Question 1) G alpha subunit is active when

Option A, it is bound to molecule of GTP.

G trimeric protein, consist of alpha, beta and gamma .

In normal condition alpha subunit is present in bound with GDP . This keeps alpha subunit in associated with beta and gamma subunit and inactivation of G protein.

When signal is present, GDP is replaced with GTP and het activated by selearikn if alpha subunit form beta and gamma subunit.

Question 2) option E

Lipoyllysin

Lipoic acid has lysine group at active site

During reaction, first acetyl group is transferred to two, then liopyl group if lipoic acid. This liopyl group directly transfer acetyl group to coA.

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