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Cytokines are chemical messengers produced in response to a stimulus. Which of the following cytokines is...

Cytokines are chemical messengers produced in response to a stimulus. Which of the following cytokines is involved in the inflammation of autoimmune diseases?

a. interleukins

b. tumor necrosis factor

c. chemokines

d. interferon

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Answer #1

ANSWER: a) Interleukins

EXPLANATION:

  • Interleukins belong to a group of cytokines which are synthesized by Macrophages, monocytes, B-lymphocytes etc.
  • Interleukins involved in Autoimmune diseases are IL-17, IL-21 and IL-22.
  • TNF: Tumor necrosis factor; produced by Macrophages/monocytes and is involved in acute inflammation. It plays a significant role in providing resistance to infections and cancers.
  • Interferons: They combat viral infections by interfering with transcription of viral nucleic acid.
  • Note: IL-1 and IL-6 are involved in fever.
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