Question

Inflammation and tumorigenesis are linked. Give 3 examples showing the linkage and why for each of...

Inflammation and tumorigenesis are linked. Give 3 examples showing the linkage and why for each of those examples?

Homework Answers

Answer #1
  • Inflammation and oncogenes activation both leads to activation of inflammatory transcription factors within the tumors.
  • Inflammation leads to cell proliferation and survival through cox-2.
  • Inflammation also causes cancer related inflammation through chemokines.
  • Inflammation after causing cell proliferation causes metastasis and malignant cell migration.
  • CD4T count increases due to inflammatory tumour promotion.
  • An example for inflammatory tumour promotion leading to cancer is Pylori infection causes, gastric cancer. Hepatitis B infection causes hepatic cancer. Colon cancers could be seen due to Schistosoma infection.
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