Question

what is the removal mechanism for neurotransmitter Dopamine? Would it be the VMAT (Vesicular Mono-Amine Transporter) that is involved in the removal of dopamine to send it to the synaptic cleft for removal

Answer 1

The removal of neurotransmitter Dopamine is carried out by Dopamine transporter ( DAT), which is a membrane spaning protein that performs the function of pumping Dopamine out of the synaptic cleft into the cytosol. In the cytosol, Dopamine is stored in vesicles for later usage. The clearing of Dopamine from synapses is carried out by Dopamine transporter (DAT), followed by depositing it into surrounding cells. This leads to termination of the signals of the neurotransmitter.