1. There are two alleles at a locus: A and P. Assume these two alleles are in Hardy-Weinberg equilibrium. Assume also that Allele P has a frequency of exactly 1% in the population. Given this information, what is the frequency of AP heterozygotes in the population?
2. You are studying an allele A that governs parasite resistance in a large population of rabbits.
You observe that different combinations of A and a produce phenotypes that have different fitnesses due to differences in parasite resistance.
The fitness of AA is 0.38, the fitness of Aa is 0.38, while the fitness of aa is 0.24.
A allele starts at a frequency of 0.67.
Assuming Hardy-Weinberg equilibrium except for differences in selection, what will the frequency of A be in the next generation?
1)
1% indicate 1/100
frequency of allele P = 1/100 or 0.01
frequency of allele A = 99/100 or 0.99
frequency of heterozygote ( AP) 2pq = 2X 0.01X0.99
=0.0198
2)
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