Question

1. positive selection ensures that mature T cells can recognize self MHC molecules. a. True b. False

2. the master gene regulator found in Th1 cells can negatively regulate the master gene regulator found in Th2 cells. a. True b. False

3. Treg cells secrete cytokines that are good at inducing inflammation. a. True b. False

4. anergic cells cannot be activated. a. True b. False

5. CTL cells can be subdivided based on the types of cytokines they secrete. a. True b. False

Answer 1

1. positive selection ensures that mature T cells can recognize self MHC molecules. a. True

2. the master gene regulator found in Th1 cells can negatively regulate the master gene regulator found in Th2 cells. a. True

3. Treg cells secrete cytokines that are good at inducing inflammation. b. False (Treg cells secrete cytokines which are anti-inflammatory in nature such as TGF-β, IL-10)

4. anergic cells cannot be activated. b. False (Anergic T cells can be reactivated by cytokines

5. CTL cells can be subdivided based on the types of cytokines they secrete. b. False (CTL secretes cytokines such as gamma-IFN, TNF-α and TNF-β which directly inhibits viral replication and activates the macrophages. Instead of CTL cells, T-helper cells are subdivided into Th1 and Th2 cells based on the types of cytokines they secrete)