Question

1) Superantigens cross link T cells with APC in a polyclonal, non specific fashion. a. True b. False

2) cross presentation of antigens in a special circumstance only allowed in cells that become licensed to activate Tc cells. a. True b. False

3) central tolerance refers to T cells that become anergic in centrally located tissues. a. True b. False

4) activated Th cells express the cytokine IL-2 and the high affinity receptor for IL-2.  a. True b. False

Answer 1

1.

True, because when a T cell is activated by the antigen. The antigen activates only specific T cells and causes monoclonal activation.where as when a superantigen activates T cells. It does so non specifically giving rise to polyclonal T Cell activation.

2.

True, These antigen presenting cells are specially for this purpose.

3.False,

​​because the central tolerance is the T cells that become anergic in the primary lymphoid tissue. For T cell it is the thymus where as for B cells it is the Bone marrow.

4.False,

because IL-2 is produced mainly by the activated CD8+ and CD4+ cells though to a small extent by the Th cells. It's receptors called IL-2R are present on the CD8+ T cells, regulatory T cells, NK cells and other T cells but not only by the Th cells