Shown below is DNA sequence on the coding strand for a structural gene.
5'-AGGACTAAATGACATGGACACTAACTAGTTGGAAGCTAACCC... -3'
How many amino acids does the polypeptide encoded by this sequence contain?
A. 7
B. 8
C. 6
D. 12
E. 10
ANSWER :
If the base sequence of DNA on its coding strand is :-
5' AGGACTAAATGACATGGACACTAACTAGTTGGAAGCTAACCC 3'
then, the corresponding mRNA nucleotide sequence would be :-
5' AGG ACU AAA UGA CAU GGA CAC UAA CUA GUU GGA AGC UAA CCC 3'
Since, each codon of m-RNA that codes for a specific amino acid contains three sequence of nitrogenous base, except three terminal codons that would stop the translation process to proceed further. The UGA is a stop codon which located at the fourth position in the m-RNA sequence. Hence only first 3 amino acids would be produce during the translation.
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