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a) In humans albinism is a recessive trait. Two persons (male and female) are albino because...

  1. a) In humans albinism is a recessive trait. Two persons (male and female) are albino because of homozygosity for recessive genes, but together, they produce only normal offspring. How can this be most simply explained? (5pts)
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Answer #1

Albinism is an autosomal recessive disease, which means that a person will be albino if only he/she has both recessive alleles (aa) for the gene. When two carrier parents produce offsprimg, there is a 1 in 4 (1/4) chance that the offspring will show the disease.

Two persons, both of which are albino, producing normal offspring can be explained by the concept of penetrance of the gene in a population.

In such a case, a person might have both the alleles for a recessive disorder but may not show the clinical symptoms because of modifiers, epistatic genes, suppressors or environmental effect.  

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