Question

1. Which following statement is NOT correct, regarding ketone bodies? A. Acetyl CoA is the immediate...

1. Which following statement is NOT correct, regarding ketone bodies?
A. Acetyl CoA is the immediate precursors of ketone bodies
B. Brain and heart can use ketone bodies as energy source
C. Both Leucine and Isoleucine are ketogenic amino acids
D. Ketone bodies can be only produced in liver

2. Glycerol-phosphate acyltransferase (GPAT) can be activated by
A. Insulin
B. Epinephrine
C. AMPK
D. Glucagon

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Homework Answers

Answer #1

1: incorrect option is C

Both Leucine and Isoleucine are ketogenic amino acids.

As ,Ketone bodies can be utilized as fuel in the heart, brain and muscle.

Ketone bodies are produced mainly in the mitochondria of liver cells, and synthesis can occur in response to an unavailability of blood glucose, such as during fasting.

The net effect of increased production and decreased utilization of acetyl-CoA is an increase in the concentration of acetyl-CoA, which is the precursor of ketone body.

2:Glycerol-3-phosphate acyl transferase (GPAT) is activated by insulin.Our results reveal a link between the lipogenic effects of insulin and microsomal GPAT3 and GPAT4, implying their importance in glycerolipid biosynthesis.

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