Question

Explain two reasons why ATP hydrolysis releases a high amount of free energy relative to other...

Explain two reasons why ATP hydrolysis releases a high amount of free energy relative to other biochemical reactions in a cell as it pertains to its phosphate group.  

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Answer #1

The reasons which makes ATP hydrolysis release high amount of free energy as the orthophosphate molecular ion which is stabilized by multiple resonance structures making products more stable than the reactants which are ADP +Pi and ATP respectively. The second reason is that the electronic repulsion between 3 phosphate group also contributes to the high energy and instability which is stabilized by release of energy and Pi through the hydrolysis.

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