Question

The four types of resolution response after implantation of a device/biomaterial are

(i) extrusion,

(ii) resorption,

(iii) integration, and

(iv) encapsulation.

What type of resolution response occurs with each of the following device/biomaterial (note: in some case, more that one type of resolution is possible): a. Splinter

b. Degradable tissue engineering scaffold

c. Titanium bone screw

d. Degradable meniscal arrow (used to repair meniscal tears)

e. Breast implant

f. Artificial heart valve leaflet

g. Catheter h. Surface scar tissue (scab)

Answer 1

A)a splinter is a small fragment from a large object inserted into the body either accidentally or purposely the resolution response may be extrusion it may automatically extruded if it may be encapsulated which leads to infection followed by fever.

B) degradable tissue engineering scaffold

It may be resorped as it is biodegradable or it may be extruded as foreign body

C))ttitanium bone screw it either gets ingrated as titatanium it has the capacity to ingrate with bone which is known as osseointegration .

It may also br extruded as foreign particle

D) degradable meniscal arrow it may be resorped a after its work is done it resorp or is encapsulated

E)breast implants they may be encapsulated or resorped after their function is over

F) artificial heart valve leaflet it may be encapsulated .

G)catheter is extruded as it is present exterior ly

H)surface scar tissue is always extruded