Question

Define and describe the autophagy process within a cell

Define and describe the autophagy process within a cell

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Autophagy in cell=autophagy is a normal physiological process in the body that deals with destruction of cells in the body.

Autophagy is a process of self -digestion.

autophagy process within a cell -During autophagy ,sequestration begins with the formation of a phagosome.

phagosome form de novo in the cytoplasm from a cup -shaped membrane that expands into a double membrane bound autophagosome surrounding a portion of the cytoplasm.

The autophagosome may fuse with an endosome.The product of endosome -autophagosome fusion is called as an amphisome.

The completed autophagosome fuses with a lysosome ,which supplies acid hydrolases.The enzymes in the resulting compartment,an autolysosome ,break down the inner membrane from the autophagosome and degrade the cargo.The resulting macromolecules are released and recycled in the cytosol.

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