Question

Continuing from Q2, redraw your diagram after resolution of the Holliday junctions: a) in the same...

Continuing from Q2, redraw your diagram after resolution of the Holliday junctions:
a) in the same plane b) in opposite planes

Which resolutions would result in genetic recombination of flanking markers? Show this on your diagram.

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Answer #1

Resolution of the holliday junction in the same plane:

a)

This model involves the stage of crossing over and recombination of the genes by the combination of the two different chromosomal strands during recombination. The Flankning markers are the genes A,B and a and b which recombine with each other. This includes the branch point X migration model which involves the recombination of the genes.

b)

The opposite planes for the holliday junctions:

This involves the recombination of the genes in two planes X and Y during the crossing over stage.

The resolving model involves the rotation of the chromosomal strand by 180o during recombination.

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