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The structures of the amino acids leucine and isoleucine are shown: If a mutation in the...

The structures of the amino acids leucine and isoleucine are shown:




If a mutation in the DNA of a globular enzyme changed all of the leucine amino acids to isoleucine, predict how the relative position of the amino acid in the tertiary structure of the protein would be affected when the protein is placed in an aqueous solution. If the leucine amino acids were found within the active site of the enzyme, discuss the effect this change is likely to have on enzymatic function.

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