Question

Indicate true (T) and false (F) statements below regarding the nucleus and nuclear protein transport.

1. The inner and outer nuclear membranes are continuous with each other, yet maintain distinct protein compositions.

2. A protein without a nuclear localization signal can be transported into the nucleus by binding to a protein with NLS.

3. The endoplasmic reticulum lumen is continuous with the nuclear interior.

4. Many proteins shuttle in and out of the nucleus.

Answer 1

answer 1 - true statement

The inner and outer nuclear membranes are continuous with each other, yet maintain distinct protein compositions as the inner membrane contain the proteins which interact and bind with the chromatin and outer membrane protein , nuclear envelope protein give rigidity

answer 2 - true statement

this can be true if the size of the proteins together dnt exceed the allowing limit of protein through nuclear pore complex

answer 3 - true statement

The endoplasmic reticulum lumen is continuous with the nuclear interior , means the space between the inner and outer nuclear membranes is directly connected with the lumen of the ER

answer 4 - true statement

Many proteins shuttle in and out of the nucleus as shuttling help in transport of the protein and some time protein carry rna as well.

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