Question

pleasse i need a good explaination

whats the isoforms and what does it mean by ( there are various isoforms of actin amd tubulins) and how the isoformes contain actin and tubulin, whats the role of both

Answer 1

Both actin and tubuline have isoforms, that mean they are not unique single proteins, they have many variations instead. For example actin isoforms are almost identical, there are 6 of them and only vary in a few of their amino acid residues, and they are expressed by different genes in the genome. Four of the six isoforms of actin are expressed only in muscle, some of them only in smooth muscle, others only in cardiac muscle, but the other 2 actin isoforms are widely expressed in many tissues. This points at the idea that the 4 isiforms expressed in muscle acomplish specific functions surrounding contraction, while the other 2 work for housekeeping genes. The different tubulin isoforms play roles in cell internal transport, motile organelles and mitosis.