Question

1. Types of genes that cause cancer when mutated include all of the following EXCEPT:

A. cell-cycle control genes.

B. pro-apoptotic genes.

C. growth-factor receptor genes.

D. DNA repair genes.

E. Actually, mutations of any of these can lead to cancer.

2. Genes involved in cancer include all of the following EXCEPT:

A. telomerase, which rebuilds telomeres.

B. angiogenic genes (promote growth of blood vessels).

C. DNA repair genes

D. signal-transduction genes, such as ras.

E. Actually, all of these are involved in cancer.

6. Which of the following is NOT part of the sequential mutation model of the development of colorectal cancer?

A. mutations that promote metastasis

B. ras mutation promoting cell division

C. p53 tumor-suppressor mutation leading to malignancy

D. mutation in telomerase promoting tissue invasion

E. Actually, all of these are part of the model

Answer 1

Please find the answers below:

Answer 4: Choice E (All these biomolecular factors are associated with the regulation of cell cycle control, either at transcriptional or translational levels, hence regulate cancerous growth in cells)

Answer 5: Choice E (All of these genes are related to the cell cycle control and progression in the cells, hence directly involved in oncogenesis)

Answer 6: Choice E (All metastatic and other relevant mutations that lead to cancer can promote colorectal cancer)