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Describe how many opioid receptor subtypes exist. Then, use Multalign to generate an image of multiple...

Describe how many opioid receptor subtypes exist.

Then, use Multalign to generate an image of multiple sequence alignment results.

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Answer #1

1) The opioid system has been divided into four subtypes that work on endogenous peptides :

  • MOP - mu opioid peptide receptor - inhibits respiration and modulates the hormonal and neurotransmitter releases
  • DOP - delta opioid peptide receptor - supraspinal and spinal analgesia and similar modulation of the releases
  • KOP - kappa opioid peptide receptor - psychotomimetic effects and slow gastrointestinal transit
  • NOP - nociceptin orphanin FQ peptide receptor - modulates pain
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