Question

Helicobacter pylori is the bacteria that causes stomach ulcers. When scientists first proposed that Helicobacter pylori might be associated with stomach ulcers, other scientists were very skeptical of their conclusions. One of the researchers eventually consumed a sample and documented the effects, dramatically showing that the bacterium could cause gastrointestinal symptoms.

3a. Name and describe the temperature and pH “-phile” designation for H. pylori. Explain your answers.

3b. In order to cause ulcers H. pylori needs to overcome the environment of the stomach (it produces a neutralizing enzyme), stick to the stomach lining and burrow into the stomach tissue. What structures does H. pylori have that allow it to do these things? Explain

Answer 1

3a. H.pylori for infecting the lining of the stomach must be presented with temperature and pH designation that enables it to multiply on the gastric linin.This is around 30oC -37oC and pH of around 4-5

3b.H.pylori after it eneters the host reach the epithelial cell surface of the stomach in flagellary movement and attaches to the surface through various interaction with the receptors of the host.This leads to colonization and after which produce toxins and yrease which neutralizes the acidic pH of the stomach .The disturbs the gastric lining and makes it more susceptible to attack by the high acidic gastric acids leads to ulcers.