Question

Some vaccines are administered multiple times over a period of months. Refer to the biology of B cells to explain why multiple exposures—rather than a single exposure—to the vaccine antigens provides better immunity to whatever pathogen the vaccine represents.

Answer 1

There are some vaccines which require more than one dose which means they need multiple exposures. The B-cells are also known as B-lymphocytes and they help in secreting antibodies the moment they encounter foreign antigens. With the repeated dose of the vaccines, the memory B-cells helps in recognizing the antigens the moment the body encounters it next time. The memory B cells are formed in the germinal centers after the primary infection and helps in starting a robust antibody mediated immune response. As kids are given the vaccines it initially helps in providing immunity but gradually its impact reduces. In order to boost the immune system and increase the production of B-cells on encountering antibodies, multiple vaccinations is important. With multiple exposure to antigens, the B-cells helps delivering a quick response to the foreign antigens the moment it is encountered.