Question

Part 2: Click on the box that says “mRNA.” You are presented with a gene that contains a regulatory region and a transcribed region. Your goal is to maximize the rate of transcription of the gene into mRNA..

1. What three factors maximize the rate of transcription from the gene?

2. Click on the check box on the bottom right. Increase the concentration and affinity of negative transcription factors to high, while decreasing the concentration and affinity of positive transcription factors to low. What effect does this have on the rate of transcription? ( _____ / 2 pts)

Answer 1

1) The three factors that maximize the rate of transcription in a gene are listed below,

• Increase in the concentration and affinity of enhancers or positive transcription factors
• Decrease in the concentration of negative transcription factors or repressors
• The presence or absence of physiological stimuli

2) Increase the concentration and affinity of negative transcription factors to high, while decreasing the concentration and affinity of positive transcription factors to low decreases the rate of transcription.