Part 1: Click on the box that says “Expression.” You are presented with a gene that contains a regulatory region and a transcribed region. Your goal is to produce 3 proteins from each of three genes. The proteins are indicated by the shapes in the box at the top right. You need to successfully transcribe each gene, and then translate the message from the gene into a protein using your knowledge of how these processes work.
GENE 1 Questions
What two components are required to initiate transcription of the gene? To which region of the gene do they bind?
What is the product of successful transcription of Gene 1?
What component is necessary to produce a protein from the transcript?
Suppose Gene 1 produces a protein involved in the development of the eye. In the simulation, what are two ways that you can prevent production of Gene 1 protein in other parts of the body? At what points in the progression from gene to protein do these methods act (i.e., what processes do they prevent)?
GENE 2 and 3 Questions
How does initiation of transcription differ in Gene 2 and Gene 3 as compared to Gene 1?
Transcription factor and RNA Polymerase is required to initiate the transcription of gene. They bind to the promoter region.
The mRNA is the succeful product of gene 1's transcription
tRNA ( transfer RNA), mRNA ( messenger RNA), ribosomes are used to produce a protein from transcript.
The specific transcription factor are found in the specific cells which allows transcription of gene in specific cells only. Similarly repressor repress the gene in other part of the cell. These methods acts as the transcription initiation part.
Gene 2 and gene 3 transcription takes place in presence of transcription factor that is specific to gene 2 and gene 3 promoter. But the different transcription factor are found for gene 3 promoter. That's why the initiation step of transcription is differ in different genes.
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