Question

LDL cholesterol is taken into the cell by receptor-mediated endocytosis.

True or false

Answer 1

The receptor-mediated endocytosis is highly selective process of import of specific large molecules into the cells. The process occurs by binding of a specific protein or molecule (cholesterol) to a surface receptor on the membrane. The binding results in formation of a pocket in the plasma membrane and the cholesterolmolecule is squeezed inside the cell and the plasma membrane surface sealed. The Low density lipoproteins (LDLs) are removed by receptor mediated endocytosis pathway. The liver cells contain the LDL receptor B – 100 and many other cells also contain this receptor. Inside a cell the LDL is broken down to protein and free cholesterol. Therefore, the given statement is true.