Question

35: the identification and study of genes important for the cell cycle in budding yeast has provided great insight into our understanding of the unregulated cell cycle in cancer cells. Why is budding yeast such a useful model sysetm for studying the cell cycle?
a. As budding yeast progress through the cell cycle, they naturally express a GFP-tagged protein that is visible by fluorescence microscopy
b. it is easy to visualize yeast by scanning the electron microscopy, which is helpful tool for performing generic screens
c. The genes involved in the cell cycle in budding yeast are very different from the human genes involved in the cell cycle
d. The cell cycle in budding yeast can be easily visualized using a light microscope and mutants with defects in cell cycle genes can be easily isolated

19. A mitotic spindle____.
a. is formed during S phase of the cell division.
b. is essential for aligning the chromosomes to the center of the spindle during prophase.
c. Is assembled during prophase of a cell cycle.
d. has two components: astral spindle microtubules and chromosomal spindle fibers.
20. The lymphoid progenitor cells can proliferate to replenish their self and also produce T cells, B cells and NK cells. The latter three will undergo terminal differentiation. What is the potency of the lymphoid progenitor cells?
A. Impotent
B. Multipotent
C. Pluripotent
D. Totipotent
21. Cytokinesis could be blocked if cells are
A. Two of these are true
B. Depleted for GTP
C. treated with actin-depolymerizing drugs
D. Depleted for kinesin with antibody treatment

Answer 1

35. Option d. Yeast cells can divide into large number and their buds gets attached into them.A single mutation in the gene for the division can lead to abnormal growth of the cells.And the budding can be easily visualize with light microscope.

19. Option c.Mitotic spindle is made up of microtubules.It is assembled in the first stage of mitotic division known as prophase.Mitotic spindles attach to the kinetochores and help to align the chromosomes during metaphase.

20. Option b.The cells ability to differentiate into other cells are known as multi potency.Pleuripotent cells can give rise to any other cells in the body.Totipotent cells give rise placenta and embryo.Impotent is the disability of a man to erect.

21. Option d.Cytokines can be blocked by using monoclonal antibodies which combine with the cytokine and block the receptor.