What are the five steps in the urea cycle (include names of the enzymes, and structures of intermediates). b. What is the molecular connection between the urea cycle and the citric acid cycle? c. What are the major control mechanisms of the urea cycle?
CPS I is the rate limiting enzyme.
And fumarate is the connecting link between urea cycle and citric acid cycle. This fumrate enters the TCA cycle and converts into malate then Oxaloacetic acid and then to aspartate. This aspartate further enters the urea cycle.
The urea cycle is regulated mainly by 2 factors:
1.) Amount of urea cycle enzymes
2.) Concentration of acetyl-glutamate and ornithine
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