.Why is the apicoplast a useful target for anti-apicomplexan drug therapy?
A.apicomplexans are fully resistant to all other drugs, so this is the target of last resort
B.disabling the functions of the apicoplast would prevent asexual replication of parasites
C.humans do not have apicoplasts, so side effects of new drugs would not be severe
D.both B and C
Answer- D.both B and C . ( disabling the functions of the apicoplast would prevent asexual replication of parasites and humans do not have apicoplasts, so side effects of new drugs would not be severe )
The apicoplast is a plastid of endosymbiotic, eukaryotic algal ancestry in apicomplexans such as Plasmodium. It has genes mainly involved in metabolism but it also plays important role in parasitic asexual life cylce . Also gene products of apicoplast are different from host protein i.e. human which make apicoplast best target for for anti-apicomplexan drug therapy
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