Question

Which of the following most accurately depicts dysbiosis? Group of answer choices

A 20-year-old individual's microbiome is analyzed and found to be very different than their microbiome at 1 year of age

A person experiences a dramatic change in their intestinal microbiota that leads to chronic diarrhea and intestinal pain

Two friends tested their microbiome and found that their microbial compositions were very different

A man assessed his own microbiome and found that it contained known pathogens such as Staphylococcus aureus, Escherichia coli, Enterococcus faecalis, and Clostridium difficile

A woman experiences fever, chills, and painful sores on her hands

Answer 1

Answer: A man assessed his own microbiome and found that it contained known pathogens such as Staphylococcus aureus, Escherichia coli, Enterococcus faecalis, and Clostridium difficile. This most accurately depicts dysbiosis since in dysbiosis, an imbalance in gut microbiota occurs. Mostly gram negative bacteria grow extensively as compared to gram negative. Reduction of usefull bacteria occurs and harmful ones grow faster. Though, option second is also close because dysbiosis lead to diarrhea and stomach cramps. However, a dramatic change is not observed.

Option 1 is incorrect since it is a normal phenomenon of microbial colonization. Also, option 3 is wrong as no two humans can have identical composition of gut microbiota. Fever and chills aren't usual symptoms of dysbiosis. so last option is also eliminated.