Question

Doesn't a microarray experiment tell us exactly the same thing as an RNA-Seq experiment? A) Yes...

Doesn't a microarray experiment tell us exactly the same thing as an RNA-Seq experiment?

A) Yes

B) Yes, but one technique doesn’t give us any indication regarding the amount of a given transcript

C) Yes, but one technique doesn’t tell us much about mRNA processing

D) No, they are completely different experiments

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Answer #1

Correct answer is : B.Yes, but one technique doesn’t give us any indication regarding the amount of a given transcript.

Reason:  The difference between RNA-Seq and microarrays is that RNA seq allows for full sequencing of the whole transcriptome while microarray allows for sequencing of only predefined transcripts/genes through the process of hybridization.Also, in microarray getting the  amount of transcripts /transcript copy number information is a problem but in RNA-seq,there is high sensitivity of for genes that are either expressed in low or high amounts.

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