Question

Q 16, Here is the coding region for two strains of the same bacterial species:

Strain 1: 5' - GTACTAACCATATTCACC - 3'

Strain 2: 5' - GCTACTAACCATATTCACC - 3'

There should only be one correct answer. Thank you!

Assume this region is translated. Select the true statement:

1. This is a deletion mutation that results in frameshift.

2. This is a substitution mutation resulting in missense.

3. This is an insertion mutation that is silent.

4. This is an insertion that results in frameshift.

5. This is a base substitution that is nonsense.

6. This is a base substitution that is silent.

Answer 1

Here is the coding region for two strains of the same bacterial species:

Strain 1: 5' - GTACTAACCATATTCACC - 3'

Strain 2: 5' - GCTACTAACCATATTCACC - 3'

This is an example of Insertion that results into frameshift mutations because

Well when this sequence is translated the proteins are altered due to change in the coding sequence of the amino acids.

After transcription of both strains.

Strain A 5' CAUGAUUGGUAUAAGUGG 3'

Strain B 5' GCAUGAUUGGUAUAAGUGG 3'

The first amino acid coded by strain A will be Histidine and that of strain B will be Arginine.

Hence the proteins are affected drastically.

Option 4 is correct