Question

For the following E.coli genotype   trpR- trpP+ trpO+ trpE+ / trpR+ trpP+ trpOc trpE- the production...

For the following E.coli genotype  

trpR- trpP+ trpO+ trpE+ / trpR+ trpP+ trpOc trpE-

the production of the first enzyme (trpE) in the tryptophan operon is

constitutive

inducible

zero

repressible

Homework Answers

Answer #1

the production of enzyme (trpE) in this is Repressible.

Genes under Oc operator are expressed constitutively but trpE gene under Oc operator is mutated. So only trpE will be expressed which is present on the first Operon and it is under wild-type operator. Active repressor can bind to wild-type operator and can repress the expression in the presence of Tryptophan.

As presence of Tryptophan makes represser active. So enzyme will be preduced when there is no Tryptophan and expression will be repressed in presence of Tryptophan.

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