Question

1. Irreversible effects of toxin or poison can result in the following except
   1. Teratogen - causes birth defects
   2. Hypersensitivity –exaggerated response to some chemical agents
   3. Carcinogen - causes cancer
   4. Mutagen - causes chromosome damage
   5. Reproductive hazard - damage to reproductive system
2. Toxicant-induced alteration of the regulatory or maintenance function of the cell can result in the following except.
   1. Impaired internal maintenance
   2. Dysregulation of ongoing cellular function
   3. Drug interaction in a case of polypharmacy
   4. Impaired external maintenance
   5. Dysregulation of gene expression
3. Which of the following is NOT TRUE about the toxicological actions of toxin/poison?
   1. They may increase body functions (for example, increasing the heart rate or sweating),
   2. They may decrease body functions (sometimes to the point of stopping them entirely, like breathing).
   3. Exposure to toxins can cause more severe and symptoms, including head and body tremors, muscle spasms or stiffness, muscle weakness or paralysis, rapid heart rate, difficulty breathing, seizures, convulsions, or coma.
   4. They can cause generalized multiple organ failure

Answer 1

1. Irreversible effects of toxin or poison can result in the following except for

d. Mutagen - causes chromosome damage. Because toxins interact with proteins to cause a rapid effect.

2. Toxicant-induced alteration of the regulatory or maintenance function of the cell can result in the following except.

e. Dysregulation of gene expression. Because gene expression takes time to induce effect, and toxins must act very rapidly.

3. Which of the following is NOT TRUE about the toxicological actions of toxin/poison?

d. They can cause generalized multiple organ failure. Because toxins specifically act in a type of proteins that not every organ will have.