If the d and e genes are 24cM apart in humans, and a DE/de woman mates with a de/de man, what is the probability that their first child will have the genotype DdEe?
Question:
Answer:
Male : de/de
Female: DE/de
Alleles |
de |
de |
DE |
DdEe |
DdEe |
de |
ddee |
ddee |
Probability of getting DdEe offspring in absence of linkage =2/4 = 0.5
But in presence of linkage, map distance between d and e = 24cM
Probability of getting DdEe offspring = (Probability of getting DdEe offspring in absence of linkage – probability of conversion DE into De or dE
= (0.5- (0.24/2)
= (0.5-0.12)
= 0.38
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